The European Platform for the Responsible Use of Medicines in Animals (EPRUMA - www.epruma.eu) was established in 2005 with the mission of promoting the responsible use of medicines in animals in the EU. EPRUMA issued in 2008 "Best-practice framework for the use of antimicrobials in food-producing animals” (see section “Good practice” on the left side)! The initiative comprises the following stakeholders: